Molecular BiologyNucleic Acids ResearchPeer-reviewed
Antisense RNA C9orf72 Hexanucleotide Repeat Associated With Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Forms A Triplex-Like Structure and Binds Small Synthetic Ligand
Leszek Błaszczyk, Marcin Ryczek, Bimolendu Das…·Agnieszka Kiliszek
This study determines the crystal structure of antisense C9orf72 hexanucleotide repeat RNA with and without a ligand, revealing its triplex-like structure and ligand binding mechanism.
7 citations