Olga Vafaeva

Regulation of hippocampal excitatory synapse development by the adhesion G-protein coupled receptor Brain-specific angiogenesis inhibitor 2 (BAI2/ADGRB2)

This study shows that BAI2 regulates glutamatergic synapse and PSD95-associated spine development in hippocampal neurons, with distinct effects compared to other BAI family members.

Neurosphere culture derived from aged hippocampal dentate gyrus

This paper introduces a novel neurosphere culture system using NPCs from adult and aged mice to study adult-born NPCs and their role in hippocampal function and aging.

Fidgetin-like 2 is a novel negative regulator of axonal growth and can be targeted to promote functional nerve regeneration after injury.

This study identifies FL2 as a negative regulator of axonal growth and shows that targeting it with siRNA promotes nerve regeneration in a rodent model of peripheral nerve injury.