Cancer BiologybioRxivPreprint
Multi-omics analysis reveals integrin α3-dependent mechanisms of Zika virus oncolytic activity in pediatric neural tumor
DOI 10.64898/2026.05.01.722162
Author
University of SouthamptonORCID 0000-0002-1912-9758Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Matt Sherwood, Ben Nicholas, A.G. Bailey…·Rob M. Ewing
This paper identifies 19 ZIKV peptides presented on paediatric brain tumour cells via HLA-I, showing their potential for developing epitope-specific immunotherapies.
Matt Sherwood, Thiago Mitsugi, Carolini Kaid…·Rob M. Ewing
This study investigates the immunogenic response of paediatric brain tumour cells to oncolytic Zika virus infection using multiomics approaches, identifying TNF-alpha as a key mediator of oncolytic efficacy and immune activation.