Shuai Wang

The paper identifies three new families of archaeal extrachromosomal elements and shows their relatedness is due to horizontal gene transfer, not common ancestry.

The paper introduces MODIFI, a tool for detecting DNA modifications in metagenomes, and identifies ECE-host linkages in environmental and human samples.

SpecImmune uses long-read sequencing to accurately genotype immune-related genes, showing improved accuracy over existing methods and revealing new genetic patterns.

The paper introduces PStrain-tracer, a software package to track microbial strain engraftment during FMT using shotgun metagenomic data, revealing strain-specific engraftment patterns and failure determinants.

The paper identifies genetic variants and transcripts associated with glycemic traits by analyzing exome-array data from 144,600 individuals, highlighting tissue-specific roles in glucose regulation.

This study identifies rare genetic variants associated with type 2 diabetes using exome sequencing of 20,791 cases and 24,440 controls, and provides a Bayesian framework to improve variant prioritization.