Author

Tom Huxford

San Diego State UniversityORCID 0000-0002-1939-7373Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Gourisankar GhoshiD· 1 shared Myung Soo KoiD· 1 shared Shandy ShahabiiD· 1 shared Tapan BiswasiD· 1 shared Xiang-Yang Zhong· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperImmunology

Gourisankar GhoshORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintJul 1, 2026

Cryo-EM reveals alternative modes of dimerization driving activation of IKK

Tapan Biswas, Shandy Shahabi, Xiang-Yang Zhong…·Gourisankar Ghosh

This paper uses cryo-EM to show that IKK2/β adopts distinct dimeric conformations that regulate its activation through structural plasticity and interactions with NEMO and polyubiquitin.

DOI 10.64898/2026.06.29.735262

cryo-EMexperimental assay

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