Author

Randall E. Burton

Broad InstituteORCID 0000-0002-1981-9484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alexandra E. GouldiD· 1 shared Alison CameroniD· 1 shared Amirshayan Chadeganipour· 1 shared Blanche C. IpiD· 1 shared Carly R. Langan· 1 shared Daniel P. BondesoniD· 1 shared David E. RootiD· 1 shared David Husselbee· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexandra E. GouldORCID

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1 paper

Recent·Most cited

Dynamic inositol pyrophosphate synthesis is a targetable therapeutic opportunity in ovarian cancer.

Daniel P. Bondeson, David Husselbee, Saoirse Hanbury, Amirshayan Chadeganipour, Gabriel Mesa, Alison Cameron, Janhavi Y. Sawant, Carly R. Langan, Tuhina Bhattacharya, YuhJong Liu, Hajer Siala, Erin M Swanson, Mustafa Kocak, Karthik Srinivasan, Blanche C. Ip, , Todd R. Golub

This study evaluates strategies to inhibit XPR1 in ovarian cancer, showing that IP6K inhibitors effectively mimic XPR1 inhibition by blocking phosphate efflux and reducing tumor burden in xenograft models.

bioRxiv · Aug 26, 2026 · PreprintCancer Biology