Femke Heindryckx

This study evaluates irinotecan's effects on intestinal motility, permeability, and histopathology in rats and Caco-2 cells, finding increased motility, permeability, and tissue damage.

The paper introduces CombiCTx, an assay for screening anti-cancer drug combinations by simulating drug diffusion gradients in a tumor-like environment to assess interactions and cytotoxic effects.

This study compares the chemotoxic effects of idarubicin and doxorubicin in HCC models, finding differential impacts on fibrosis, stellate cell activation, and ER-stress pathways.