Metaproteomics Reveals Potential Mechanisms by which Dietary Resistant Starch Supplementation Attenuates Chronic Kidney Disease Progression in Rats
Boris L. Zybailov, Galina V. Glazko, Yasir Rahmatallah, Dmitry S. Andreyev, Taylor McElroy, Oleg K. Karaduta, Stephanie D. Byrum, Lisa Dwyer Orr, Alan J. Tackett, Samuel G. Mackintosh, Ricky D. Edmondson, Dorothy A. Kieffer, Roy Joseph Martin, Sean H. Adams, Nosratola D. Vaziri, John M. Arthur
The paper uses metaproteomics to analyze cecum contents in CKD rats with and without resistant starch, revealing shifts in gut microbiota and host proteins associated with improved CKD outcomes.
PLoS ONE · Jan 30, 2019Peer-reviewedSystems Biology