Author

Zongchao Han

University of North Carolina at Chapel HillORCID 0000-0002-2019-395XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

Julie Munsoor· 2 shared Min Zheng· 2 shared Yong‐Su KwoniD· 2 shared Alex I. SmirnoviD· 1 shared Alice Yang ZhangiD· 1 shared Christopher Wu· 1 shared L Wang· 1 shared Mary Kaufmann· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

Julie Munsoor

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 17, 2026

Melanin regulates mitochondrial dynamics, metabolism and inflammatory signaling to protect the retina

Md Jahirul Islam, Yong-Su Kwon, Julie Munsoor…·Zongchao Han

This study shows that melanin in retinal pigment epithelium regulates mitochondrial structure, metabolism, and inflammation, protecting against light-induced retinal damage.

DOI 10.64898/2026.05.15.724948

mousebulk RNA-seq

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Pharmacology & ToxicologyAdvanced SciencePeer-reviewedMay 30, 2024

Polydopamine Nanoparticles as Mimicking RPE Melanin for the Protection of Retinal Cells Against Blue Light-Induced Phototoxicity

Yong‐Su Kwon, Julie Munsoor, Mary Kaufmann…·Zongchao Han

This study uses polydopamine nanoparticles to mimic RPE melanin and protect retinal cells from blue light-induced phototoxicity in Nrf2-deficient mice.

23 citationstop 1%

mouseimaging

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Molecular BiologyACS NanoPeer-reviewedOct 21, 2022

Melanin Nanoparticles as an Alternative to Natural Melanin in Retinal Pigment Epithelium Cells and Their Therapeutic Effects against Age-Related Macular Degeneration

Yong‐Su Kwon, Min Zheng, Alice Yang Zhang, Zongchao Han

This study demonstrates that PEGylated-synthetic melanin nanoparticles can substitute for natural melanin in retinal pigment epithelium cells and provide antioxidant protection against oxidative stress in age-related macular degeneration.

70 citationstop 1%

mouseexperimental assay

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