Fernando Souza-Fonseca-Guimarães

The paper introduces SM3DD, a 3D spatial transcriptomics analysis method, and finds differences in transcript distances between normal and SARS-CoV-2 patient lung tissues.

This study uses spatial transcriptomics to identify placental dysfunction signatures in SARS-CoV-2 infected pregnancies, revealing altered gene expression related to hypoxia, oxidative stress, and preeclampsia-like pathways.

This paper develops a spatial multi-omics platform to analyze immune responses in SARS-CoV-2-infected lung tissues, revealing macrophage infiltration and spatial heterogeneity in cytokine and interferon signaling.