Kirsty Renfree Short

This study shows glycaemic variability, not just hyperglycaemia, increases heart muscle dysfunction and myocardial injury risk in diabetes using genetic and experimental models.

This study identifies TNF and IL-1β as key drivers of endothelial dysfunction and coagulopathy in acute SARS-CoV-2 infection using in vitro and in vivo models.

This study shows that AVE0991, a Mas receptor agonist, reduces cytokines and viral titres in vitro but worsens disease in vivo in viral respiratory infections.

This study investigates how influenza A virus infection alters host cell glycosylation, identifying changes in sialic acid levels and glycan structures, and linking these to viral mechanisms and host responses.

This study compares SARS-CoV-2 Omicron variants' effects on nasal epithelial ciliated cells, finding increased tropism and dysfunction in BA.5 and XBB compared to BA.1 and ancestral virus.

This study identifies trace-level cytokines in PASC patients linked to cardiovascular symptoms and shows their impact on cardiomyocyte function using nanotechnology detection.

This study investigates the role of pulmonary vagal sensory neurons in influenza pathogenesis, finding that their ablation or inhibition worsens clinical outcomes but reduces lung pathology.

This study uses spatial transcriptomics to identify placental dysfunction signatures in SARS-CoV-2 infected pregnancies, revealing altered gene expression related to hypoxia, oxidative stress, and preeclampsia-like pathways.

This paper develops a spatial multi-omics platform to analyze immune responses in SARS-CoV-2-infected lung tissues, revealing macrophage infiltration and spatial heterogeneity in cytokine and interferon signaling.

This study shows that SARS-CoV-2 spike and orthoreovirus p15 proteins induce fusion between neurons and glial cells across species, leading to syncytia and organelle exchange.

The paper generates the first chromosome-length annotated genomes and transcriptomes of black and mute swans, revealing immune system limitations and plumage-related genetic differences.