Author

Yang Hai

University of California, Santa BarbaraORCID 0000-0002-2039-5367Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yang Hai1 paper

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:fungi (other)· 1

Frequent Co-Authors

Shaonan LiuiD· 2 shared Matthew JenneriD· 1 shared Mia E. Foran· 1 shared Nazia AucklooiD· 1 shared Y. T. Candace HoiD· 1 shared Zainab BatooliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersBiochemistry

Shaonan LiuORCID

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2 papers

Recent·Most cited

Biosynthesis of the alpha-D-Mannosidase Inhibitor (-)-Swainsonine

Shaonan Liu, Zainab Batool, Yang Hai

This study reconstitutes the biosynthesis of (-)-swainsonine, revealing key enzymes and mechanisms for its stereochemical formation and enabling new glycosidase inhibitor synthesis.

Nature Chemical Biology · Aug 11, 2025Peer-reviewedBiochemistry

Biochemical dissection of a fungal highly reducing polyketide synthase condensing region reveals basis for acyl group selection.

Mia E. Foran, Nazia Auckloo, Y. T. Candace Ho, Shaonan Liu, Yang Hai, Matthew Jenner

This study investigates the acyl group selection mechanism in fungal hrPKS condensing regions through in vitro reconstitution and mass spectrometry, revealing substrate recycling and kinetic parameters as key factors.

Chemical Science · Jan 1, 2025Peer-reviewedBiochemistry