BiochemistryChemical SciencePeer-reviewed
Biochemical dissection of a fungal highly reducing polyketide synthase condensing region reveals basis for acyl group selection.
Mia E. Foran, Nazia Auckloo, Y. T. Candace Ho…·Matthew Jenner
This study investigates the acyl group selection mechanism in fungal hrPKS condensing regions through in vitro reconstitution and mass spectrometry, revealing substrate recycling and kinetic parameters as key factors.
8 citations