Author

Y. T. Candace Ho

University of WarwickORCID 0000-0002-8520-9801Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:fungi (other)· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Matthew JenneriD· 3 shared Józef Romuald LewandowskiiD· 2 shared Mia E. Foran· 2 shared Christopher D. FageiD· 1 shared Fabrizio AlbertiiD· 1 shared Guenther WinkelmanniD· 1 shared Joseph D. NewmaniD· 1 shared Lona M. AlkhalafiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersBiochemistry

Matthew JennerORCID

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3 papers

Recent·Most cited

Structural and biochemical characterisation of an iterative GCN5-related N-acetyltransferase required for fungal siderophore tailoring

Joseph D. Newman, Y. T. Candace Ho, Christopher D. Fage, Guenther Winkelmann, Lona M. Alkhalaf, Józef Romuald Lewandowski, Fabrizio Alberti, Matthew Jenner

This study characterizes SidG, a GNAT enzyme in Aspergillus fumigatus, revealing its iterative acetylation mechanism for siderophore biosynthesis.

bioRxiv · Sep 28, 2026 · PreprintBiochemistry

Molecular characterisation of the acyltransferase-acyl carrier protein interface in a fungal highly reducing polyketide synthase.

Mia E. Foran, Y. T. Candace Ho, Józef Romuald Lewandowski, Matthew Jenner

The paper characterizes the AT:ACP interface in a fungal polyketide synthase using mutagenesis, mass spectrometry, and simulations to reveal structural and functional insights.

RSC Chemical Biology · Dec 9, 2025Peer-reviewedBiochemistry

Biochemical dissection of a fungal highly reducing polyketide synthase condensing region reveals basis for acyl group selection.

Mia E. Foran, Nazia Auckloo, Y. T. Candace Ho, Shaonan Liu, Yang Hai, Matthew Jenner

This study investigates the acyl group selection mechanism in fungal hrPKS condensing regions through in vitro reconstitution and mass spectrometry, revealing substrate recycling and kinetic parameters as key factors.

Chemical Science · Jan 1, 2025Peer-reviewedBiochemistry