Author

Mark J. Burk

ORCID 0000-0002-2045-2691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Anna LechneriD· 1 shared Ashley M. KretschiD· 1 shared Bethany K. OkadaiD· 1 shared Christopher J. RosarioiD· 1 shared Douglas A. MitchelliD· 1 shared Gabriella Costa Machado da CruziD· 1 shared Jacob Stuart Lamson· 1 shared Jasmine Mikesell· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Anna LechnerORCID

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Author profile →

2 papers

Recent·Most cited

Overcoming Immune Checkpoint Inhibitor Resistance via Potent and Selective Dual αvβ6/8 Inhibitors Based on Engineered Lasso Peptides

Anna Lechner, Peter A. Jordan, Gabriella Costa Machado da Cruz, Jacob Stuart Lamson, Jessica Gordon, Bethany K. Okada, Kelsey Anderson, Rajan R. Chaudhari, Christopher J. Rosario, Jasmine Mikesell, Scott A. McPhee, Mark J. Burk

Journal of the American Chemical Society · Sep 2, 2025Peer-reviewedCancer Biology

Cell-Free Biosynthesis to Evaluate Lasso Peptide Formation and Enzyme-Substrate Tolerance

Yuanyuan Si, Ashley M. Kretsch, Laura M. Daigh, Mark J. Burk, Douglas A. Mitchell

This study uses cell-free biosynthesis to produce lasso peptides, demonstrating their sequence diversity and enzyme-substrate tolerance.

Journal of the American Chemical Society · Apr 6, 2021Peer-reviewedSynthetic Biology