Author

Samad Amini

Biogen (United States)ORCID 0000-0002-2063-6220Unclaimed ORCID profile · follow to get notified of new preprints

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1 Assay:protein structure· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

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Simone SciabolaiD· 1 shared Ye WangiD· 1 shared

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2026-2026 · peak 1/yr

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1 shared paperMolecular Biology

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1 paper

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Molecular BiologybioRxivPreprintMay 27, 2026

Affinity Fine-Tuning of Boltz-2: An Open Framework for Protein-Ligand Potency Prediction in Drug Discovery

Samad Amini, Simone Sciabola, Ye Wang

This paper introduces an open framework to fine-tune Boltz-2 for protein-ligand potency prediction, improving its utility in drug discovery with project-specific data.

1 citation

protein structuredeep learning

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