Author

Simone Sciabola

Biogen (United States)ORCID 0000-0003-1448-3608Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:software / tool· 2 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Christine Lawrence· 1 shared Daniel R. Caffrey· 1 shared Dario A. Cruz· 1 shared Hualin Simon XiiD· 1 shared Jason D. HughesiD· 1 shared Qing Na CaoiD· 1 shared Robert V. StantoniD· 1 shared Samad AminiiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperBioinformatics

Christine Lawrence

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 27, 2026

Affinity Fine-Tuning of Boltz-2: An Open Framework for Protein-Ligand Potency Prediction in Drug Discovery

Samad Amini, Simone Sciabola, Ye Wang

This paper introduces an open framework to fine-tune Boltz-2 for protein-ligand potency prediction, improving its utility in drug discovery with project-specific data.

1 citation

protein structuredeep learning

𝕏 PostBluesky

BioinformaticsPLoS ONEPeer-reviewedJan 22, 2021

PFRED: A computational platform for siRNA and antisense oligonucleotides design.

Simone Sciabola, Hualin Simon Xi, Dario A. Cruz…·Robert V. Stanton

PFRED is a software tool for designing and analyzing antisense oligonucleotides and siRNA, offering customizable design criteria and open-source access.

48 citations

experimental assaysoftware / tool

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