NeurosciencebioRxivPreprint
Microglial GSDMD-Mediated Pyroptosis Drives Neuroinflammation in Parkinson's Disease
Mengmeng Wang, Yuedong Wang, Tianyi Wang…·You Yin
This study shows that microglial pyroptosis via the CASPASE-1/GSDMD pathway drives neuroinflammation and dopaminergic neuron loss in Parkinson's disease, suggesting GSDMD as a therapeutic target.
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