Author

Jacob Emil Petersen

University of CopenhagenORCID 0000-0002-2116-1626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:simulation· 1

Frequent Co-Authors

Aslihan ShenoliD· 1 shared James Andrew McCammoniD· 1 shared Michael LückmanniD· 1 shared Thomas M. FrimureriD· 1 shared Thue Walter SchwartziD· 1 shared Wen MaiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperBiophysics

Aslihan ShenolORCID

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1 paper

Recent·Most cited

Constitutive activation and allosteric mechanisms underlying Gi/Gq signaling bias in SUCNR1 revealed by AlphaFold-based modeling and enhanced sampling simulations

Aslihan Shenol, Jacob Emil Petersen, Michael Lückmann, Thomas M. Frimurer, James Andrew McCammon, Thue Walter Schwartz, Wen Ma

This study uses AlphaFold and simulations to show human SUCNR1 spontaneously adopts active conformations and exhibits constitutive signaling, while murine SUCNR1 requires agonist for activation.

bioRxiv · Jun 8, 2025 · PreprintBiophysics