Mitochondrial priming in human germ cell tumors is dependent on MCL1 and BCL2L1
Sirli Anniko, Sonia Khan, Jamie RJ Morton, Wajiha Iftikhar, Ana Teixeira, Craig R. G. Willis, Kirsten Riches‐Suman, Krzysztof Poterlowicz, Steven D. Shnyder, Rod Thomas Mitchell, Sherif F. El‐Khamisy, Simon J. Allison, Peter K. Nicholls
This study identifies MCL1 and BCL2L1 as critical for GCT survival and shows their inhibition enhances response to DNA damaging agents.
bioRxiv · Sep 26, 2026 · PreprintCancer Biology