Chloe S. Chernoff

Chemogenetic inhibition of the noradrenergic locus coeruleus promotes the development of risk-taking decisional strategies and selectively enhances motor impulsivity in females

This study shows that inhibiting LC-NA neurons accelerates risk-taking decision strategies and enhances motor impulsivity in female rats during a gambling task.

Compulsive coping behaviour, developed predominantly by sign-trackers, is exacerbated by chronic atomoxetine

This study shows that sign-tracking rats develop compulsive drinking behaviors, which are worsened by chronic atomoxetine, suggesting a role for noradrenergic mechanisms in compulsive coping.

Accumbal cholinergic interneurons regulate decision making or motor impulsivity depending on latent task state

This study investigates how accumbal cholinergic interneurons (aCINs) influence decision making and motor impulsivity in the rat gambling task, showing sex-specific effects based on task state.

Biological Sex Influences the Contribution of Sign-Tracking and Anxiety-Like Behaviour toward Remifentanil Self-Administration

This study shows that biological sex moderates how personality traits like anxiety and sign-tracking affect remifentanil self-administration in rats.