Author

Yves Delneste

Centre National de la Recherche ScientifiqueORCID 0000-0002-2142-596XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Agnès Guichet· 1 shared Alban C. ZiegleriD· 1 shared Céline BeauvillainiD· 1 shared Charline MiotiD· 1 shared Christophe BlanquartiD· 1 shared Coralie MallebrancheiD· 1 shared Estelle ColiniD· 1 shared Franck Geneviève· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Agnès Guichet

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Biallelic WDR91 variants cause a neurodevelopmental disorder through impaired endosomal maturation and autophagy dysregulation

Nathalie Merillon, Magalie Barth, Alban C. Ziegler, Patrick Van Bogaert, Sophie Guéden, Estelle Colin, Agnès Guichet, Gwendal Poussereau, melissa giroudoux, Franck Geneviève, Isabelle Pellier, Coralie Mallebranche, Yves Delneste, Céline Beauvillain, Charline Miot

The paper identifies biallelic WDR91 variants causing a neurodevelopmental disorder by impairing endosomal maturation and autophagy.

medRxiv · Apr 3, 2026 · PreprintGenetic & Genomic Medicine

IL-27 neutralization promotes pro-inflammatory macrophage polarization and improve response to immune checkpoint blockade

Quentin Glaziou, Laëtitia Basset, Sènan Mickaël D'Almeida, Pascale Pignon, Christophe Blanquart, Yves Delneste, Julie Tabiasco

This study shows that blocking IL-27 reduces CD39 expression in tumor cells and enhances anti-PD-L1 therapy effectiveness.

bioRxiv · Sep 13, 2024 · PreprintImmunology