TET2 regulates the neuroinflammatory response in microglia
Alejandro Carrillo-Jiménez, Özgen Deniz, Maria Victoria Niklison-Chirou, Rocío Ruiz, Karina Bezerra Salomão, Vassilis Stratoulias, Rachel Amouroux, Ping Kei Yip, Anna Vilalta, Mathilde Cheray, Alexander Michael Scott-Egerton, Eloy Rivas, Khadija Tayara, Irene García-Domínguez, Juan García‐Revilla, , Miguel Ángel Burguillos
This study shows TET2 regulates microglial inflammatory responses through NF-κB-dependent pathways and metabolic changes, suggesting it as a target for neurodegenerative diseases.
Cell Reports · Oct 1, 2019Peer-reviewedNeuroscience