John Stegmayr

Deep learning for rapid and reproducible histology scoring of lung injury in a porcine model

This study evaluates the reproducibility of human histology scoring for ARDS in a porcine model and demonstrates that CNNs can automate the process with acceptable performance.

Isolation of high yield and quality RNA from human precision-cut lung slices for RNA-sequencing and computational integration with larger patient cohorts

The paper presents a method for isolating high-quality RNA from human precision-cut lung slices, enabling RNA-seq analysis and computational integration with larger patient cohorts.

Galectin-3, A Novel Endogenous Trem2 Ligand, Regulates Inflammatory Response and Aβ Fibrilation in Alzheimer’s Disease

This study identifies galectin-3 as a novel endogenous TREM2 ligand that regulates microglial activation and Aβ fibrillation in Alzheimer’s disease.