Gene Y. Fridman

Spatiotemporal Abstraction Theory: Re-Interpretation of Localized Cortical Networks

This paper proposes a theory of spatiotemporal abstraction to explain how localized cortical networks produce stable, concept-level representations from noisy inputs and addresses implications for neural implants and artificial networks.

Why Meaning Survives Noise: The Spatiotemporal Abstraction Theory

This paper proposes a theory of spatiotemporal abstraction to explain how the brain extracts meaning from noisy input, demonstrating it with spectrograms from cochlear implants.

Field-Sensitive Axon Initial Segment Polarization by IonicDirect Current Dissociates Gain Modulation from TemporalStructure in Cortical Circuits

This paper introduces ionic direct current (iDC) as a neuromodulation method that adjusts cortical gain without directly evoking spikes, preserving temporal structure and native neural dynamics.

Galvanic vs. Pulsatile Effects on Decision-Making Networks: Reshaping the Neural Activation Landscape

This study compares galvanic and pulsatile stimulation effects on a decision-making neural network model, finding that low-amplitude galvanic stimulation produces more distributed responses, while high-amplitude galvanic stimulation can directly activate or block neurons.

Peripheral direct current suppresses physiologically evoked nociceptive responses at the spinal cord in rodent models of pain

This study shows direct current stimulation suppresses nociceptive responses in rodent pain models, suggesting broader clinical applications for chronic pain treatment.

Pulsatile electrical stimulation creates predictable, correctable disruptions in neural firing

This study uses computational modeling to explain how pulsatile electrical stimulation affects neural firing rates and shows that these effects can be predicted and corrected.