Author

Chen-Song Zhang

SLAC National Accelerator LaboratoryORCID 0000-0002-2213-0899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Brian K. KobilkaiD· 2 shared Evan S. O’BrieniD· 2 shared Haoqing WangiD· 2 shared Kaavya Krishna KumariD· 2 shared Amal El Daibani· 1 shared Antoine KoehliD· 1 shared Brandon J. KennedyiD· 1 shared Chris H. Habrian· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiochemistry

Brian K. KobilkaORCID

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2 papers

Recent·Most cited

BiochemistryNaturePeer-reviewedJul 3, 2024

Negative allosteric modulation of the μ-opioid receptor

Evan S. O’Brien, Vipin Ashok Rangari, Amal El Daibani…·Brian K. Kobilka

This paper identifies a negative allosteric modulator of the μ-opioid receptor that blocks agonist activity and enhances naloxone efficacy, offering potential for safer opioid overdose reversal.

54 citationstop 2%

humanexperimental assay

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BiophysicsNaturePeer-reviewedApr 17, 2024

Step-wise activation of a Family C GPCR

Kaavya Krishna Kumar, Haoqing Wang, Chris H. Habrian…·Brian K. Kobilka

The paper proposes a step-wise activation model for metabotropic glutamate receptor subtype 5, supported by structural and fluorescence imaging data of different activation states.

54 citationstop 2%

experimental assay

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