Author

Diane Yang

Harvard UniversityORCID 0000-0002-2229-0622Unclaimed ORCID profile · follow to get notified of new preprints

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Diane Yang1 paper

Biology Disciplines

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Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Anthony John IafrateiD· 2 shared Chengzhuo GaoiD· 2 shared Dawn R. MitchelliD· 2 shared Edwin ZhangiD· 2 shared Elizabeth M. CoddiD· 2 shared Stefan T. KaluziakiD· 2 shared Aaron N. HataiD· 1 shared Abigail Elizabeth SmithiD· 1 shared

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2025-2026 · peak 1/yr

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10 top collaborators · 42 mutual co-author links

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2 shared papersSystems Biology

Anthony John IafrateORCID

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2 papers

Recent·Most cited

Systematic Targeting of Protein Complexes with Molecular COUPLrs

Diane Yang, Stefan Andrew Harry, Harrison Byron Chong, Neha Khandelwal, Edwin Zhang, Natalie Shannon Nordenfelt, Nicholas J. Chen, Christine Lee, Stefan T. Kaluziak, Elizabeth M. Codd, Samay Trivedi, Magdy Gohar, Giovan McKnight, Dawn R. Mitchell, Maolin Ge, , Liron Bar‐Peled

The paper introduces molecular COUPLrs to systematically target protein complexes, identifying new glue classes and their interactions in cancer cell lines.

Cancer Discovery · Jul 27, 2026Peer-reviewedSystems Biology

Reversible Downregulation of HLA Class I in Adenoid Cystic Carcinoma

Annie Li, Bianca L Gonda, Elizabeth M. Codd, Adam von Paternos, Dawn R. Mitchell, Markus D. Herrmann, Prinjali Kalyan, Samantha E. Flynn, Thuc Q Dzu, Chengzhuo Gao, Edwin Zhang, Julia J Mendel, Julia C Thierauf, Peter M. Sadow, Thomas Denize, , Anthony John Iafrate

This study identifies low HLA/B2M class I expression in ACC tumors and shows it can be reversed by interferon-ψ or STING agonists, suggesting a path for immunotherapy.

Journal for ImmunoTherapy of Cancer · Apr 1, 2025Peer-reviewedCancer Biology