Author

Wioleta Milena Zelek

Cardiff UniversityORCID 0000-0002-2230-3550Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

B. Paul MorganiD· 2 shared Andreas KlosiD· 1 shared Andreas TiedeiD· 1 shared Arno FenskeiD· 1 shared Emma Arndt· 1 shared James A. L. MilleriD· 1 shared James K. L. HoltiD· 1 shared Jennifer E. SpillaneiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersImmunology

B. Paul MorganORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Platelets Link Coagulation and Complement in Regulating Placental Vascular Development

Arno Fenske, Lisa Schumann, Ulrike Peters-Bernard, Kerstin Flächsig-Schulz, Emma Arndt, Andreas Klos, B. Paul Morgan, Wioleta Milena Zelek, Andreas Tiede, Markus Abeln

The paper identifies placental microthrombi as structures that link coagulation and complement to regulate placental vascular development, showing that platelet activation via PAR4 is necessary for localized complement activation.

bioRxiv · Sep 11, 2025 · PreprintImmunology

Complement biosynthesis in human brain: Insights from single-nucleus transcriptomics of hippocampus.

Van Dien Nguyen, Matthew Bright, You Zhou, B. Paul Morgan, Wioleta Milena Zelek

This study uses single-nucleus RNA sequencing to map complement gene expression in human hippocampus, identifying cell-type-specific patterns and changes in Alzheimer's disease.

bioRxiv · May 6, 2025 · PreprintNeuroscience

Lymphocyte alterations and elevated complement signalling are key features of refractory myasthenia gravis

Katherine Claire Dodd, Kirsten L. Baillie, James K. L. Holt, Maria Isabel Leite, Lijing Lin A, Peter West, James A. L. Miller, Jennifer E. Spillane, Stuart Viegas, Wioleta Milena Zelek, Jon D. Sussman, Madhvi Menon

This study identifies lymphocyte alterations and elevated complement signaling as key features of refractory myasthenia gravis, with implications for treatment strategies.

bioRxiv · Mar 15, 2025 · PreprintImmunology