Abigail L. Pfaff

This study uses polygenic and transcriptional risk scores to analyze psychiatric and cognitive symptoms in Parkinson's disease, finding distinct associations between genetic and transcriptional risks and symptom progression.

The paper identifies RNA biomarker signatures in whole blood transcriptomes of MND patients compared to controls, highlighting differentially expressed genes and associated molecular pathways.

The paper investigates how mitochondrial function affects ALS severity but not risk, identifying specific genetic and expression factors linked to disease progression.

This study analyzes intronic RNA-Seq data from Parkinson's Disease patients over time, revealing significant changes in nascent transcription specific to the disease.