Author

Kao-Jung Chang

Boston Children's HospitalORCID 0000-0002-2238-7387Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Cong-Hui YaoiD· 1 shared Hao CheniD· 1 shared Jiaojiao GuoiD· 1 shared Marcia C. HaigisiD· 1 shared Qianqian CheniD· 1 shared Yang ShiiD· 1 shared Zhennan Shi· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Cong-Hui YaoORCID

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1 paper

Recent·Most cited

The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for proper mitochondrial function

Hao Chen, Zhennan Shi, Jiaojiao Guo, Kao-Jung Chang, Qianqian Chen, Cong-Hui Yao, Marcia C. Haigis, Yang Shi

This study identifies METTL15 as the enzyme responsible for m4C839 methylation in human 12S mt-rRNA and shows its critical role in mitochondrial function.

Journal of Biological Chemistry · May 5, 2020Peer-reviewedMolecular Biology