Molecular BiologyJournal of Biological ChemistryPeer-reviewed
The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for proper mitochondrial function
Hao Chen, Zhennan Shi, Jiaojiao Guo…·Yang Shi
This study identifies METTL15 as the enzyme responsible for m4C839 methylation in human 12S mt-rRNA and shows its critical role in mitochondrial function.
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