Single molecule methylation profiles of cell-free DNA in cancer with nanopore sequencing
Billy T. Lau, Alison Figueroa Almeda, Marie C. Schauer, Madeline McNamara, Xiangqi Bai, Qingxi Meng, Mira A. Partha, Susan M. Grimes, HoJoon Lee, Gregory M. Heestand, Hanlee P. Ji
The paper develops a nanopore sequencing strategy to measure cfDNA methylomes in cancer patients, enabling longitudinal monitoring during treatment.
Genome Medicine · May 3, 2023Peer-reviewedGenomics