Author

Jessica L. Giordano

Columbia University Irving Medical CenterORCID 0000-0002-2265-0691Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Ronald J. WapneriD· 2 shared Ajit Muley· 1 shared Alicia BrandtiD· 1 shared Anne O’Donnell‐LuriaiD· 1 shared Ben WeisburdiD· 1 shared Benjamin CurralliD· 1 shared Bernie DevliniD· 1 shared Bradford C. PowelliD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Ronald J. WapnerORCID

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2 papers

Recent·Most cited

Roles for RERE in lymphatic endothelial cell proliferation and survival, and human cystic lymphatic malformations

Daniella Rogerson, Ajit Muley, Jessica L. Giordano, Zoe Vogel, Ronald J. Wapner, Carrie J. Shawber

This study identifies RERE as a regulator of lymphatic endothelial cell proliferation and survival, linking its loss to cystic lymphatic malformations through altered Notch signaling and lymphangiogenic gene expression.

bioRxiv · Mar 24, 2024 · PreprintCell Biology

Systematic evaluation of genome sequencing for the assessment of fetal structural anomalies

Chelsea Lowther, Elise Valkanas, Jessica L. Giordano, Harold Z. Wang, Benjamin Currall, Kathryn O’Keefe, Emma Pierce‐Hoffman, Nehir Edibe Kurtas, Christopher W. Whelan, Stephanie P. Hao, Ben Weisburd, Vahid Jalili, Jack M. Fu, Isaac Wong, Ryan L. Collins, , Michael E. Talkowski

This study evaluates genome sequencing as a single diagnostic approach for fetal structural anomalies, showing it detects nearly all variants from standard tests and provides higher diagnostic yield than individual tests.

bioRxiv · Aug 12, 2020 · PreprintGenomics