Carrie J. Shawber

This study shows that combining gamma secretase inhibitor with radiotherapy and checkpoint blockade therapy reprograms the tumor microenvironment to enhance antitumor immunity.

This study identifies RERE as a regulator of lymphatic endothelial cell proliferation and survival, linking its loss to cystic lymphatic malformations through altered Notch signaling and lymphangiogenic gene expression.

This study identifies distinct roles for Notch4 and canonical Notch signaling in embryonic dermal lymphangiogenesis using mouse models.

This study shows that overactive p53 in lymphatic endothelial cells causes lymphatic defects in mice and human tissues, and normalizing p53 restores lymphatic function.