Colleen S. Deane

This paper develops a network-based atlas of human skeletal muscle aging using transcriptomic data from 1,675 biopsies and multiple single-cell technologies, revealing gene modules and interactions associated with aging and load status.

The paper establishes international consensus criteria to classify ageing-related pathologies, diseases, and syndromes based on age progression, functional decline, and human evidence.

This study shows that spaceflight causes dendritic remodeling and impaired clearance of neuronal debris in adult C. elegans neurons.