Author

R. Shyama Prasad Rao

Nitte UniversityORCID 0000-0002-2285-6788Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:statistical model· 7 Organism:C. elegans· 2 Organism:human· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:fine-mapping· 1

Frequent Co-Authors

Sudeep Darbhe GhateiD· 6 shared Larina PintoiD· 4 shared Rajesh Padumane ShastryiD· 4 shared Prashanth SuravajhalaiD· 3 shared Praveenkumar K. ShettyiD· 3 shared Nagib AhsaniD· 2 shared Prakash PatiliD· 2 shared Belle Damodara ShenoyiD· 1 shared

Activity by Year

2021-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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6 shared papersBioinformatics

Sudeep Darbhe GhateORCID

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Azole resistance: Patterns of amino acid substitutions in Candida sterol 14α-demethylase

R. Shyama Prasad Rao, Larina Pinto, Rajesh Padumane Shastry, Tikam Chand Dakal, Prashanth Suravajhala, Vangal Krishnaswamy Sashindran, Sudeep Darbhe Ghate

The paper identifies common amino acid substitutions associated with azole resistance in Candida species by analyzing 2,222 resistant substitutions from literature.

bioRxiv · Jul 4, 2024 · PreprintBioinformatics

Azole resistance: Insights from Y132 substitutions in Candida sterol 14α-demethylase

R. Shyama Prasad Rao, Larina Pinto, Renuka Suravajhala, Belle Damodara Shenoy, Sudeep Darbhe Ghate

The paper investigates azole resistance in Candida by analyzing Y132 substitutions in sterol 14α-demethylase and their effects on drug binding.

bioRxiv · Nov 13, 2023 · PreprintBioinformatics

Gut feeling: Extent of virulence and antibiotic resistance genes in Helicobacter pylori and campylobacteria

R. Shyama Prasad Rao, Sudeep Darbhe Ghate, Larina Pinto, Prashanth Suravajhala, Prakash Patil, Praveenkumar K. Shetty, Nagib Ahsan

The paper analyzes virulence and antibiotic resistance genes in Helicobacter pylori and other campylobacteria, finding H. pylori has the highest number of virulence genes and unique patterns of resistance.

bioRxiv · Sep 27, 2023 · PreprintBioinformatics

Comparative genomics reveals the diversity of CRISPR-Cas systems among neonatal sepsis causing group B Streptococcus agalactiae

Sudeep Darbhe Ghate, R. Shyama Prasad Rao, Rajesh Padumane Shastry, Deepak Sebastian Pinto, Praveenkumar K. Shetty

This study analyzes CRISPR-Cas systems in S. agalactiae genomes, finding two types and their association with phylogenetic clades and anti-CRISPR elements.

bioRxiv · Sep 27, 2023 · PreprintBioinformatics

Functional network analysis identifies multiple virulence and antibiotic resistance systems in Stenotrophomonas maltophilia

Larina Pinto, Rajesh Padumane Shastry, Shivakiran Alva, R. Shyama Prasad Rao, Sudeep Darbhe Ghate

The paper identifies hub proteins in S. maltophilia's virulence and antibiotic resistance networks and evaluates phytochemicals as potential inhibitors.

bioRxiv · May 15, 2023 · PreprintBioinformatics

Prevalence and heterogeneity of antibiotic-resistant genes in Orientia tsutsugamushi and other rickettsial genomes

R. Shyama Prasad Rao, Sudeep Darbhe Ghate, Rajesh Padumane Shastry, Krishna Kurthkoti, Prashanth Suravajhala, Prakash Patil, Praveenkumar K. Shetty

The paper investigates antibiotic-resistant gene prevalence and variability in Orientia tsutsugamushi and other rickettsial genomes, finding fewer but more variable resistant genes in O. tsutsugamushi compared to other rickettsiae.

bioRxiv · Aug 17, 2022 · PreprintBioinformatics

Evolutionary dynamics of indels in SARS-CoV-2 spike glycoprotein

R. Shyama Prasad Rao, Nagib Ahsan, Chunhui Xu, Lingtao Su, Jacob C. Verburgt, Luca Fornelli, Daisuke Kihara, Dong He Xu

The paper analyzes SARS-CoV-2 spike glycoprotein sequences to show that indels are common and increasing, with implications for viral evolution and vaccine efficacy.

Evolutionary Bioinformatics · Jan 1, 2021Peer-reviewedBioinformatics