Satoshi Mitarai

Transposon insertion sequencing identifies genetic determinants of intrinsic rifamycin resistance in Mycobacterium abscessus

This study uses transposon insertion sequencing to identify genes contributing to intrinsic rifamycin resistance in Mycobacterium abscessus, revealing new mechanisms and potential therapeutic strategies.

Analysis of publicly available genomic data

This study identifies genomic mutations associated with ethambutol resistance in Mycobacterium avium-intracellulare using clinical isolates and publicly available genomic data.

Concentration-dependent suppression of macrolide resistance in Mycobacterium avium by combination therapy: an improved in vitro time-kill assay and PK/PD modelling study

This study quantifies how combination therapy with concomitant drugs suppresses macrolide resistance in M. avium using improved time-kill assays and PK/PD modeling.

Six species of non-tuberculosis mycobacteria carry non-identical 16S rRNA gene copies

The paper identifies non-identical 16S rRNA gene copies in six non-tuberculosis mycobacteria species using cloning and sequencing.