Cell BiologybioRxiv
High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension
Tsutomu Shinohara, J.-R. A. J. Moonen, Yoon Hong Chun…·Marlene Rabinovitch
The paper shows high shear stress induces endothelial-mesenchymal transition and pulmonary arterial hypertension by reducing ERG expression, which can be mitigated by ERG replenishment.