Author

Lucas‐Sebastian Spitzhorn

Heinrich Heine University DüsseldorfORCID 0000-0002-2335-6881Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Audrey NcubeiD· 2 shared James AdjayeiD· 2 shared Lars ErichseniD· 2 shared Martina Bohndorf· 2 shared Wasco WruckiD· 2 shared Chantelle ThimmiD· 1 shared Claus KordesiD· 1 shared Fatima Asar· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Audrey NcubeORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 2, 2025

Human Urine-derived SIX2-positive renal progenitor cells improve kidney injury in an IRI mouse model

Claus Kordes, Lucas‐Sebastian Spitzhorn, Martina Bohndorf…·James Adjaye

This study shows human urine-derived SIX2-positive renal progenitor cells reduce kidney fibrosis in an IRI mouse model but do not fully restore kidney function within 21 days.

DOI 10.1101/2025.07.02.662781

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintApr 8, 2019

A Comprehensive Molecular Portrait of Human Urine-derived Renal Progenitor Cells

Md Shaifur Rahman, Wasco Wruck, Lucas‐Sebastian Spitzhorn…·James Adjaye

This paper identifies and characterizes human urine-derived renal progenitor cells, revealing their molecular identity, reprogramming potential, and gene regulatory mechanisms for self-renewal and differentiation.

2 citations

humanbulk RNA-seq

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