Author

Hinde El Otmani

Utrecht UniversityORCID 0000-0002-2344-6027Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Albert HuismaniD· 1 shared Claudia TersteegiD· 1 shared Elfie I MoeskeriD· 1 shared Kazuya SakaiiD· 1 shared Masanori MatsumotoiD· 1 shared Rowan FruntiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBiochemistry

Albert HuismanORCID

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1 paper

Recent·Most cited

Plasmin-mediated cleavage of GPIbα contributes to breakdown of platelet-von Willebrand factor complexes

Rowan Frunt, Elfie I Moesker, Kazuya Sakai, Masanori Matsumoto, Albert Huisman, Claudia Tersteeg, Hinde El Otmani

This study shows plasmin cleaves GPIbα, disrupting platelet-VWF complexes, but not VWF itself, and suggests GPIb shedding may be plasmin-mediated in TTP.

bioRxiv · Mar 25, 2026 · PreprintBiochemistry