Author

Karnyart Samnuan

Imperial College LondonORCID 0000-0002-2361-6954Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

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Approach:experimental assay· 1

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Anna K. BlakneyiD· 1 shared Paul F. McKayiD· 1 shared Robin J. ShattockiD· 1 shared

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2022-2022 · peak 1/yr

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1 shared paperMolecular Biology

Anna K. BlakneyORCID

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1 paper

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Molecular BiologyF1000ResearchPeer-reviewedMar 18, 2022

Design-of-Experiments In Vitro Transcription Yield Optimization of Self-Amplifying RNA

Karnyart Samnuan, Anna K. Blakney, Paul F. McKay, Robin J. Shattock

This study optimizes in vitro transcription (IVT) for long self-amplifying RNA (saRNA) using design of experiments, identifying key factors like magnesium and NTP interactions that maximize RNA yield.

36 citations

experimental assay

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