NeurosciencebioRxivPreprint
UBE3A and transsynaptic complex NRXN1-CBLN1-GluD1 in a hypothalamic VMHvl-arcuate feedback circuit regulates aggression
Yi Nong, David C. Stoppel, Mark A. Johnson…·Matthew P. Anderson
The paper identifies a hypothalamic feedback circuit involving UBE3A and the NRXN1-CBLN1-GluD1 complex that regulates aggression, showing how autism-related genetic defects impair this circuit.
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