Gernot Riedel

Reproducible social phenotyping of 5xFAD mice in the Agora maze (Sociobox)

The paper validates a new social behavior test for mice, showing wild-type mice can recognize strangers among 5 partners and 5xFAD mice show no deficit at 6-8 months.

The Icelandic mutation APPA673T on amyloid-β plaque burden in the 5xFAD Alzheimer model

This study investigates the effect of the APPA673T mutation on amyloid-β plaque burden in 5xFAD mice, finding a significant reduction in plaque size but not in soluble Aβ levels.

The effect of the Icelandic mutation APPA673T in the line 66 model of tauopathy

This study investigates the effect of the APPA673T mutation on tau pathology and behavior in L66 tau transgenic mice, finding no significant modulation of tau pathology or behavioral deficits.

Mouse Exploratory behaviour in the open field with and without NAT-1 EEG device: Effects of MK801 and scopolamine

This study evaluates the impact of NAT-1 EEG devices on mouse behavior in the open field test with and without pharmacological treatments, finding minimal behavioral effects.

Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 model of frontotemporal dementia

This study examines the effects of dietary methionine restriction on cognitive and behavioral phenotypes in a mouse model of frontotemporal dementia, finding improvements in motor function and memory in aged mice.

Sex differences in behaviour and molecular pathology in the 5XFAD model

The paper examines sex differences in behavior and molecular pathology in 5XFAD mice, finding sex-specific differences in amyloid levels, inflammation, and cognitive performance.

The interoceptive hippocampus: mouse brain endocrine receptor expression highlights a dentate gyrus (DG)-cornu ammonis (CA) challenge-sufficiency axis

The paper examines endocrine receptor expression in the mouse hippocampus, finding distinct distributions in dentate gyrus and cornu ammonis regions and their roles in synaptic and neurogenic processes.