Charles R. Harrington

The paper investigates the proteomic response in neuronal cells after exposure to a tau fragment, identifying pathways linked to tau pathology development.

This study investigates the effect of the APPA673T mutation on amyloid-β plaque burden in 5xFAD mice, finding a significant reduction in plaque size but not in soluble Aβ levels.

This study investigates the effect of the APPA673T mutation on tau pathology and behavior in L66 tau transgenic mice, finding no significant modulation of tau pathology or behavioral deficits.

This study investigates how inhibiting disulphide bonding in truncated tau affects its self-assembly into seed-competent structures, revealing enhanced aggregation rates and implications for tauopathy research.