Author

G. Brett Robb

New England Biolabs (United States)ORCID 0000-0002-2382-2256Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

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Jennifer L. CurcuruiD· 1 shared Megumu Yamada Mabuchi· 1 shared Paul YourikiD· 1 shared Ryan T. FuchsiD· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperMolecular Biology

Jennifer L. CurcuruORCID

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1 paper

Recent·Most cited

Cas12a trans-cleavage can be modulated in vitro and is active on ssDNA, dsDNA, and RNA

Ryan T. Fuchs, Jennifer L. Curcuru, Megumu Yamada Mabuchi, Paul Yourik, G. Brett Robb

Once activated, Cas12a degrades RNA and double-stranded DNA in trans, not only single-stranded DNA, with the amount depending on buffer, guide RNA features and which ortholog is used.

bioRxiv · Apr 8, 2019 · PreprintMolecular Biology