c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease
Abigail O. Smith, Julie A. Jonassen, Kenley M. Preval, Roger J. Davis, Gregory J. Pazour
This study shows that JNK signaling promotes cyst growth in ADPKD by enhancing cell proliferation and that inhibiting JNK reduces cyst severity.
PLoS Genetics · Dec 28, 2021Peer-reviewedGenetics