Author

Paschalis Natsidis

University College LondonORCID 0000-0002-2446-3208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:phylogenetics / evolution· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Organism:multiple species· 1 Organism:rat· 1

Frequent Co-Authors

Maximilian J. TelfordiD· 3 shared Ana Serra SilvaiD· 1 shared Gaurav D. DiwaniD· 1 shared Irepan Salvador‐MartíneziD· 1 shared John K. ColbourneiD· 1 shared Juan Carlos Gonzalez· 1 shared Laura PiovaniiD· 1 shared Mu-En Chung· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersEvolutionary Biology

Maximilian J. TelfordORCID

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3 papers

Recent·Most cited

Phylogeny and gene function integration uncovers multiple convergences in multicellular and terrestrial transitions

Gaurav D. Diwan, Paschalis Natsidis, Juan Carlos Gonzalez, Mu-En Chung, Roderic Guigó, John K. Colbourne, Maximilian J. Telford, Robert B. Russell

The paper integrates phylogenomics and functional annotations to trace gene function evolution across species, revealing convergent adaptations in multicellular and terrestrial transitions.

bioRxiv · Sep 19, 2025 · PreprintEvolutionary Biology

Support for the deuterostome clade comes from systematic errors

Ana Serra Silva, Paschalis Natsidis, Laura Piovani, Paschalia Kapli, Maximilian J. Telford

The paper investigates whether deuterostome monophyly is supported by systematic errors, finding strong support under certain conditions and ambiguity when errors are mitigated.

Current Biology · Jul 15, 2025Peer-reviewedEvolutionary Biology

Computational discovery of hidden breaks in 28S ribosomal RNAs across eukaryotes and consequences for RNA Integrity Numbers

Paschalis Natsidis, Philipp H. Schiffer, Irepan Salvador‐Martínez, Maximilian J. Telford

The paper identifies a hidden break in 28S rRNA across eukaryotes, showing its presence in protostomes and rare occurrence in vertebrates and non-animal eukaryotes, with implications for RNA Integrity Numbers.

Scientific Reports · Dec 20, 2019Peer-reviewedBioinformatics