Irepan Salvador‐Martínez

Network inference at single-cell resolution reveals morphoregulatory divergence and multilayered buffering in limb evolution

The paper compares gene regulatory networks in mouse and pig limb development to reveal conserved and divergent regulatory programs and mechanisms of developmental robustness.

C1q from C1q+ tumor-associated myeloid cells promotes resistance to T-cell engagers and CAR T-cells and is induced by LIF and glucocorticoids

This study identifies C1q from C1q+ tumor-associated myeloid cells as a key immunosuppressive factor in glioblastoma that impairs T-cell engagers and CAR T-cell efficacy, induced by LIF and glucocorticoids.

STAMP: Single-Cell Transcriptomics Analysis and Multimodal Profiling through Imaging

STAMP enables low-cost, high-throughput single-cell analysis by integrating transcriptomics and proteomics imaging, supporting both single and multimodal profiling of diverse cell types.

CeLaVi: An Interactive Cell Lineage Visualisation Tool

CeLaVi is a web-based tool for visualizing and interacting with cell lineages, integrating spatial distribution and cell properties.

Computational discovery of hidden breaks in 28S ribosomal RNAs across eukaryotes and consequences for RNA Integrity Numbers

The paper identifies a hidden break in 28S rRNA across eukaryotes, showing its presence in protostomes and rare occurrence in vertebrates and non-animal eukaryotes, with implications for RNA Integrity Numbers.

Is it possible to reconstruct an accurate cell lineage using CRISPR recorders?

This study uses simulations to evaluate the accuracy of CRISPR-based lineage reconstruction under various biological and technical conditions.