Author

Monika Kluzek

International Institute of Molecular Mechanisms and Machines Polish Academy of ScienceORCID 0000-0002-2447-699XUnclaimed ORCID profile · follow to get notified of new preprints

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Pharmacology & Toxicology· 1

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Approach:experimental assay· 1

Frequent Co-Authors

Abdelhalim AzziiD· 1 shared Abdulrahman El Sayed· 1 shared Remigiusz Adam SerwaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperPharmacology & Toxicology

Abdelhalim AzziORCID

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1 paper

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Pharmacology & ToxicologyEuropean Journal of PharmacologyPeer-reviewedApr 19, 2026

Lysosomal accumulation of Masitinib alters autophagy via pH-dependent trapping.

Abdulrahman El Sayed, Monika Kluzek, Remigiusz Adam Serwa, Abdelhalim Azzi

This study shows that masitinib accumulates in lysosomes via pH-dependent trapping, disrupting autophagy by impairing lysosomal acidification.

DOI 10.1016/j.ejphar.2026.178872

experimental assay