Author

Lance D. Dworkin

University of ToledoORCID 0000-0002-2471-5989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew L. KleinhenziD· 1 shared Apurva Chandrakant LadiD· 1 shared Benjamin W. FrenchiD· 1 shared Bivek TimalsinaiD· 1 shared David J. KennedyiD· 1 shared Deepak MalhotraiD· 1 shared Dhilhani FaleeliD· 1 shared Evgeny Yakirevich· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperMolecular Biology

Andrew L. KleinhenzORCID

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2 papers

Recent·Most cited

The IQGAP1-Claudin Cell Junction Axis in Cisplatin-induced Kidney Damage

Yusuf Barudi, Xiuzhen Fan, Kenneth W Jenkins, Shubhra Kanti Dey, Lance D. Dworkin, Evgeny Yakirevich, Mahasin A. Osman

This study investigates how cisplatin causes kidney damage by disrupting the IQGAP1-claudin cell junction axis, leading to epithelial cell dissociation and identifying potential therapeutic targets.

Cell Communication and Signaling · Mar 24, 2026Peer-reviewedCell Biology

Microcystin-LR aerosol exposure increases inflammatory drivers of asthma, Evidence of an NF-κB amplification mechanism

Joshua D. Breidenbach, Bivek Timalsina, Benjamin W. French, Lauren M. Stanoszek, John‐Paul Lavik, Irum Syed, Upasana Shrestha, Andrew L. Kleinhenz, Apurva Chandrakant Lad, Prabhatchandra R. Dube, Shungang Zhang, Dhilhani Faleel, Ronald Mark Wooten, James C. Willey, Jeffrey R. Hammersley, , David J. Kennedy

This study shows that microcystin-LR aerosol exposure worsens asthma symptoms and inflammation in mice and human airway models through an NF-κB amplification mechanism.

bioRxiv · Sep 13, 2025 · PreprintMolecular Biology